Article
Exploiting the tumor phenotype using biodegradable submicron carriers of chemotherapeutic drugs.
Critical reviews in oncogenesis - 1 Jan 2014
Geary Sean M, Salem Aliasger K
Abstract excerpt
Tumor tissues possess characteristics that distinguish them from healthy tissues and make them attractive targets for submicron carriers of chemotherapeutic drugs (CTX). CTX are generally administered systemically in free form to cancer patients resulting in unwanted cytotoxic effects and placing limitations on the deliverable CTX dose. In an effort to raise the therapeutic index of CTX there are now...
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