Article
Reconstruction of Haplotype-Blocks Selected during Experimental Evolution.
Molecular biology and evolution - 1 Jan 2017
Franssen Susanne U, Barton Nicholas H, Schlötterer Christian
Abstract excerpt
The genetic analysis of experimentally evolving populations typically relies on short reads from pooled individuals (Pool-Seq). While this method provides reliable allele frequency estimates, the underlying haplotype structure remains poorly characterized. With small population sizes and adaptive variants that start from low frequencies, the interpretation of selection signatures in most Evolve and Resequencing...
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