Article
Drosophila simulans: A Species with Improved Resolution in Evolve and Resequence Studies.
G3 (Bethesda, Md.) - 5 Jul 2017
Barghi Neda, Tobler Raymond, Nolte Viola, Schlötterer Christian
Abstract excerpt
The combination of experimental evolution with high-throughput sequencing of pooled individuals-i.e., evolve and resequence (E&R)-is a powerful approach to study adaptation from standing genetic variation under controlled, replicated conditions. Nevertheless, E&R studies in Drosophila melanogaster have frequently resulted in inordinate numbers of candidate SNPs, particularly for complex traits. Here, we contrast...
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