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Article

Prioritisation and network analysis of Crohn's disease susceptibility genes.

PloS one - 1 Jan 2014

Muraro Daniele, Lauffenburger Douglas A, Simmons Alison

Abstract excerpt

Recent Genome-Wide Association Studies (GWAS) have revealed numerous Crohn's disease susceptibility genes and a key challenge now is in understanding how risk polymorphisms in associated genes might contribute to development of this disease. For a gene to contribute to disease phenotype, its risk variant will likely adversely communicate with a variety of other gene products to result in dysregulation of common...

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Identifiers

PMID: 25268122
DOI: 10.1371/journal.pone.0108624
PMCID: PMC4182533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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