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Article

The rpoS gene is predominantly inactivated during laboratory storage and undergoes source-sink evolution in Escherichia coli species.

Journal of bacteriology - 1 Dec 2014

Bleibtreu Alexandre, Clermont Olivier, Darlu Pierre, Glodt Jérémy, Branger Catherine, Picard Bertrand, Denamur Erick

Abstract excerpt

The rpoS gene codes for an alternative RNA polymerase sigma factor, which acts as a general regulator of the stress response. Inactivating alleles of rpoS in collections of natural Escherichia coli isolates have been observed at very variable frequencies, from less than 1% to more than 70% of strains. rpoS is easily inactivated in nutrient-deprived environments such as stab storage, which makes it difficult to...

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Identifiers

PMID: 25266386
DOI: 10.1128/JB.01972-14
PMCID: PMC4248845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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