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Article

The uncertain consequences of transferring bacterial strains between laboratories - rpoS instability as an example.

BMC microbiology - 8 Nov 2011

Spira Beny, de Almeida Toledo Rodrigo, Maharjan Ram P, Ferenci Thomas

Abstract excerpt

BACKGROUND: Microbiological studies frequently involve exchanges of strains between laboratories and/or stock centers. The integrity of exchanged strains is vital for archival reasons and to ensure reproducible experimental results. For at least 50 years, one of the most common means of shipping bacteria was by inoculating bacterial samples in agar stabs. Long-term cultures in stabs exhibit genetic instabilities...

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Identifiers

PMID: 22067413
DOI: 10.1186/1471-2180-11-248
PMCID: PMC3240573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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