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Article

Escherichia coli lacking RpoS are rare in natural populations of non-pathogens.

G3 (Bethesda, Md.) - 1 Nov 2012

Snyder Emily, Gordon David M, Stoebel Daniel M

Abstract excerpt

The alternative sigma factor RpoS controls a large regulon that allows E. coli to respond to a variety of stresses. Mutations in rpoS can increase rates of nutrient acquisition at the cost of a decrease in stress resistance. These kinds of mutations evolve rapidly under certain laboratory conditions where nutrient acquisition is especially challenging. The frequency of strains lacking RpoS in natural populations...

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Identifiers

PMID: 23173085
DOI: 10.1534/g3.112.003855
PMCID: PMC3484664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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