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Article

Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models.

Molecular psychiatry - 1 Aug 2015

Lobo D S S, Aleksandrova L, Knight J, Casey D M, el-Guebaly N, Nobrega J N, Kennedy J L

Abstract excerpt

Neurobiological research supports the characterization of disordered gambling (DG) as a behavioral addiction. Recently, an animal model of gambling behavior was developed (rat gambling task, rGT), expanding the available tools to investigate DG neurobiology. We investigated whether rGT performance and associated risk gene expression in the rat's brain could provide cross-translational understanding of the...

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Source

Identifiers

PMID: 25266122
DOI: 10.1038/mp.2014.113

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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