Article
Genome-wide association study of a quantitative disordered gambling trait.
Addiction biology - 1 May 2013
Lind Penelope A, Zhu Gu, Montgomery Grant W, Madden Pamela A F, Heath Andrew C, Martin Nicholas G, Slutske Wendy S
Abstract excerpt
Disordered gambling is a moderately heritable trait, but the underlying genetic basis is largely unknown. We performed a genome-wide association study (GWAS) for disordered gambling using a quantitative factor score in 1312 twins from 894 Australian families. Association was conducted for 2 381 914 single-nucleotide polymorphisms (SNPs) using the family-based association test in Merlin followed by gene and...
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