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Proximity of Cytomegalovirus-Specific CD8+ T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals

15 Feb 2018

Abstract excerpt

Antiretroviral therapy, (ART) effectively extends the life expectancy of HIV-infected individuals, however, age-related morbidities have emerged as major clinical concerns. In this context, co-infection with cytomegalovirus (CMV) accelerates immune senescence and elevates risk for other age-related morbidities, possibly through increased inflammation. We investigated potential relationships between CMV memory...

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PMID: 29527205
DOI: 10.3389/fimmu.2018.00201

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