Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Challenge of Informed Consent and Return of Results in Translational Genomics: Empirical Analysis and Recommendations

1 Jan 2014

Abstract excerpt

Large-scale sequencing tests, including whole-exome and whole-genome sequencing (WES/WGS), are rapidly moving into clinical use. Sequencing is already being used clinically to identify therapeutic opportunities for cancer patients who have run out of conventional treatment options, to help diagnose children with puzzling neurodevelopmental conditions, and to clarify appropriate drug choices and dosing in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to Ethics in Clinical Research
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25264092
DOI: 10.1111/jlme.12151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Challenge of Informed Consent and Return of Results in Translational Genomics: Empirical Analysis and RecommendationsPMID 25264092Read ↗

Genomics really gets personal: How exome and whole genome sequencing challenge the ethical framework of human genetics researchSemantic proximity Read ↗

Return of Results in Genomic Research Using Large-Scale or Whole Genome Sequencing: Toward a New NormalSemantic proximity Read ↗

Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical DivideSemantic proximity Read ↗

The challenge of consent in clinical genome-wide testingSemantic proximity Read ↗

Next generation sequencing in psychiatric research: what study participants need to know about research findings.Semantic proximity Read ↗

Experiences with obtaining informed consent for genomic sequencingSemantic proximity Read ↗

Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issues: Table 1Semantic proximity Read ↗

Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research.Semantic proximity Read ↗

Patients' views on incidental findings from clinical exome sequencingSemantic proximity Read ↗

Tailoring the process of informed consent in genetic and genomic researchSemantic proximity Read ↗

Engaging Adolescents and Young Adults in Decisions About Return of Genomic Research Results: a mixed-methods longitudinal clinical trial protocolSemantic proximity Read ↗

Stakeholders’ Opinions on the Implementation of Pediatric Whole Exome Sequencing: Implications for Informed ConsentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.