Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The challenge of consent in clinical genome-wide testing

28 Apr 2016

Abstract excerpt

Genome-wide testing methods include array comparative genomic hybridisation (aCGH), multiple gene panels, whole exome sequencing (WE) and whole genome sequencing (WGS). Here we introduce some of the key ethical and social considerations relating to informed consent for the testing of children, particularly the management of incidental findings and variants of unknown significance.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Ethics in Clinical Research
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27127186
DOI: 10.1136/archdischild-2013-304109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The challenge of consent in clinical genome-wide testingPMID 27127186Read ↗

Genomic sequencing in newborn screening: balancing consent with the right of the asymptomatic at-risk child to be foundSemantic proximity Read ↗

A clinical perspective on ethical issues in genetic testing.Semantic proximity Read ↗

The Challenge of Informed Consent and Return of Results in Translational Genomics: Empirical Analysis and RecommendationsSemantic proximity Read ↗

Defining and managing incidental findings in genetic and genomic practiceSemantic proximity Read ↗

Professionally Responsible Disclosure of Genomic Sequencing Results in Pediatric PracticeSemantic proximity Read ↗

Genomics really gets personal: How exome and whole genome sequencing challenge the ethical framework of human genetics researchSemantic proximity Read ↗

Beyond consent: ethical and social issues in genetic testingSemantic proximity Read ↗

Disclosure of Incidental Findings From Next-Generation Sequencing in Pediatric Genomic ResearchSemantic proximity Read ↗

Genomic Testing for Human Health and Disease Across the Life Cycle: Applications and Ethical, Legal, and Social ChallengesSemantic proximity Read ↗

Management of Incidental Findings in the Era of Next-generation SequencingSemantic proximity Read ↗

Addressing the Ethical Challenges in Genetic Testing and Sequencing of ChildrenSemantic proximity Read ↗

Informed consent for BRCA1 and BRCA2 testing: what clinicians should know about the process and content.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.