Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Functional analysis of +11G > A single nucleotide polymorphisms in intron 3 of human urate transporter 1 gene].

Zhonghua nei ke za zhi - 1 Jul 2014

Lu Jie, Wang Can, Wang Yao, Li Changgui, Cui Lingling

Abstract excerpt

OBJECTIVE: We reported previously that single nucleotide polymorphisms (SNP) +11G >A in intron 3 of the human urate transporter 1 (hURAT1) gene are associated with hyperuricaemia in Han Chinese. The aim of the present study was to evaluate the effect of the variants on hURAT1 function. METHODS: The wild-type, mutant-type hURAT1 and exon 5-null hURAT1 were constructed, and respectively microinjected into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Exons
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperuricemia

Share to Introns

Share to Organic Anion Transporters

Share to Organic Cation Transport Proteins

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25264011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Functional analysis of +11G > A single nucleotide polymorphisms in intron 3 of human urate transporter 1 gene].PMID 25264011Read ↗

Multiple single nucleotide polymorphisms in the human urate transporter 1 (hURAT1) gene are associated with hyperuricaemia in Han Chinese.Semantic proximity Read ↗

[The association between single-nucleotide polymorphisms of hURAT1 and hyperuricemia in Han Chinese].Semantic proximity Read ↗

[Molecular basis of primary renal hyperuricemia : role of the human urate transporter hURAT1].Semantic proximity Read ↗

Association of the human urate transporter 1 with reduced renal uric acid excretion and hyperuricemia in a German Caucasian populationSemantic proximity Read ↗

Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.Semantic proximity Read ↗

The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia.Semantic proximity Read ↗

A case of renal hypouricemia caused by urate transporter 1 gene mutations.Semantic proximity Read ↗

<i>hURAT1</i> Transgenic Mouse Model for Evaluating Targeted Urate-Lowering AgentsSemantic proximity Read ↗

hURAT1 Transgenic Mouse Model for Evaluating Targeted Urate-Lowering Agents.Semantic proximity Read ↗

[Association of the exon 8 and intron 8 polymorphisms of the human urate transporter 1 gene with primary hyperuricemia in Chinese Han population].Semantic proximity Read ↗

[Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters].Semantic proximity Read ↗

[Polymorphisms of SLC17A1 gene and their interaction with alcohol drinking among Uygur patients with hyperuricemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.