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Article

Lipidomics reveals dysfunctional glycosynapses in schizophrenia and the G72/G30 transgenic mouse.

Schizophrenia research - 1 Nov 2014

Wood Paul L, Filiou Michaela D, Otte David M, Zimmer Andreas, Turck Christoph W

Abstract excerpt

BACKGROUND: Abnormal structural/functional connectivity has been proposed to underlie the pathophysiology of schizophrenia. However, the biochemical basis of abnormal connectivity remains undefined. METHODS: We undertook a shotgun lipidomic analysis of over 700 lipids across 26 lipid subclasses in the frontal cortex of schizophrenia subjects and hippocampus of G72/G30 transgenic mice. RESULTS: We demonstrate that...

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Identifiers

PMID: 25263995
DOI: 10.1016/j.schres.2014.08.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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