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Article

A‐to‐I editing on tRNAs: Biochemical, biological and evolutionary implications

27 Sept 2014

Abstract excerpt

Inosine on transfer RNAs (tRNAs) are post-transcriptionally formed by a deamination mechanism of adenosines at positions 34, 37 and 57 of certain tRNAs. Despite its ubiquitous nature, the biological role of inosine in tRNAs remains poorly understood. Recent developments in the study of nucleotide modifications are beginning to indicate that the dynamics of such modifications are used in the control of specific...

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PMID: 25263703
DOI: 10.1016/j.febslet.2014.09.025

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