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Article

Nicotine Alters the Proteome of Two Human Pancreatic Duct Cell Lines

19 May 2014

Abstract excerpt

CONTEXT: Cigarette smoking is a known risk factor of pancreatic disease. Nicotine--a major cigarette tobacco component--can traffic through the circulatory system and may induce fibrosis and metastasis, hallmarks of chronic pancreatitis and pancreatic adenocarcinoma, respectively. However, at the biomolecular level, particularly in pancreatic research, the effects of nicotine remain unresolved. METHODS: The...

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PMID: 25262714
DOI: 10.6092/1590-8577/2559

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