Article
Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis.
Carcinogenesis - 1 Sept 2012
Momi Navneet, Kaur Sukhwinder, Ponnusamy Moorthy P, Kumar Sushil, Wittel Uwe A, Batra Surinder K
Abstract excerpt
Despite continuous research efforts directed at early diagnosis and treatment of pancreatic cancer (PC), the status of patients affected by this deadly malignancy remains dismal. Its notoriety with regard to lack of early diagnosis and resistance to the current chemotherapeutics is due to accumulating signaling abnormalities. Hoarding experimental and epidemiological evidences have established a direct...
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