Article
Proteome alterations in pancreatic ductal adenocarcinoma.
Cancer letters - 28 Jan 2020
Pan Sheng, Brentnall Teresa A, Chen Ru
Abstract excerpt
Proteins are the essential functional biomolecules profoundly implicated in all aspects of pancreatic tumorigenesis and its progression. While common genomic factors, such as KRAS, TP53, SMAD4, and CDKN2A have been well recognized in association of pancreatic ductal adenocarcinoma (PDAC), our understanding of functional changes at the proteome level merits further investigation. Malignance associated proteome...
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