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Article

Experimental transmissibility of mutant SOD1 motor neuron disease.

Acta neuropathologica - 1 Dec 2014

Ayers Jacob I, Fromholt Susan, Koch Morgan, DeBosier Adam, McMahon Ben, Xu Guilian, Borchelt David R

Abstract excerpt

By unknown mechanisms, the symptoms of amyotrophic lateral sclerosis (ALS) seem to spread along neuroanatomical pathways to engulf the motor nervous system. The rate at which symptoms spread is one of the primary drivers of disease progression. One mechanism by which ALS symptoms could spread is...

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Source

Identifiers

PMID: 25262000
DOI: 10.1007/s00401-014-1342-7

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25262000-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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