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Article

Proximal shift of colorectal cancer. A persistent phenomenon with multiple causes, patterns and clinical implications.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Papagiorgis Petros C, Oikonomakis Ioannis, Delaportas Dionysios, Myoteri Despoina, Arkoumani Elissavet, Thalassinos Nikolaos, Zizi-Sermpetzoglou Adamantia

Abstract excerpt

A considerable change in the anatomical distribution of colorectal cancer (CRC) towards more proximal sites has been observed in Western countries within the last 6-7 decades. As a result, tumors located proximally to the splenic flexure are now accounting for 30-40% (or even more) of overall CRC cases. This proximal migration is not always representing a true increase of proximal cancer, arising from various...

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PMID: 25261642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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