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Article

Osseointegrated implant failure associated with MMP-1 promotor polymorphisms (-1607 and -519).

The International journal of oral & maxillofacial implants - 1 Jan 2000

Leite Mayra F F, Santos Maria C L G, de Souza Ana P, Line Sergio R P

Abstract excerpt

PURPOSE: Two polymorphisms in the promoter region of human MMP-1 gene, an insertion of a guanine at position -1607 and A-519G substitution, have been shown to increase the transcriptional activity of these matrix metalloproteinases (MMPs). The objective of this study was to investigate the possible relationship between these polymorphisms and early implant failure. MATERIALS AND METHODS: A sample of 104...

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Identifiers

PMID: 18807561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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