Article
Genetic susceptibility to total hip arthroplasty failure--positive association with mannose-binding lectin.
The Journal of arthroplasty - 1 Feb 2007
Malik Mohammad H A, Bayat Ardeshir, Jury Francine, Kay Peter R, Ollier William E R
Abstract excerpt
Mannose-binding lectin (MBL) may be involved in the biologic cascade of events initiated by wear debris and bacterial infection around loosened total hip arthroplasties (THAs). Individual responses to such stimuli may be dictated by genetic variation caused by single nucleotide polymorphisms (SNPs). We performed a case-control study on 4 MBL SNPs using case patients (n = 91) with aseptic loosening or deep...
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