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Laminin gene <i><scp>LAMB</scp>4</i> is somatically mutated and expressionally altered in gastric and colorectal cancers

25 Sept 2014

Abstract excerpt

Laminins are important in tumor invasion and metastasis as well as in maintenance of normal epithelial cell structures. However, mutation status of laminin chain-encoding genes remains unknown in cancers. Aim of this study was to explore whether laminin chain genes are mutated and expressionally altered in gastric (GC) and colorectal cancers (CRC). In a public database, we found that laminin chain genes LAMA1,...

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PMID: 25257191
DOI: 10.1111/apm.12309

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