Article
Association of the tumor necrosis factor -308 A/G promoter polymorphism with Tourette syndrome.
International journal of immunogenetics - 1 Dec 2014
Keszler G, Kruk E, Kenezloi E, Tarnok Z, Sasvari-Szekely M, Nemoda Z
Abstract excerpt
Several lines of evidence suggest that certain subtypes of obsessive-compulsive and tic disorders might be paediatric manifestations of post-streptococcal autoimmunity caused by cross-reactive autoantibodies. As tumor necrosis factor (TNF) is known to play a seminal role in coordinating the humoral immune response, TNF gene polymorphisms have been proposed as genetic risk factors both in obsessive-compulsive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
