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Article

Association study between functional polymorphisms in the TNF-alpha gene and obsessive-compulsive disorder.

Arquivos de neuro-psiquiatria - 1 Feb 2012

Cappi Carolina, Muniz Renan Kawano, Sampaio Aline Santos, Cordeiro Quirino, Brentani Helena, Palácios Selma A, Marques Andrea H, Vallada Homero, Miguel Eurípedes Constantino, Guilherme Luiza, Hounie Ana Gabriela

Abstract excerpt

Obsessive-compulsive disorder (OCD) is a prevalent psychiatric disorder of unknown etiology. However, there is some evidence that the immune system may play an important role in its pathogenesis. In the present study, two polymorphisms (rs1800795 and rs361525) in the promoter region of the cytokine tumor necrosis factor-alpha (TNFA) gene were genotyped in 183 OCD patients and in 249 healthy controls. The...

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Identifiers

PMID: 22311210
DOI: 10.1590/s0004-282x2012000200003
PMCID: PMC4479271

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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