Article
Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels.
Acta psychiatrica Scandinavica - 1 Apr 2015
Janelidze S, Suchankova P, Ekman A, Erhardt S, Sellgren C, Samuelsson M, Westrin A, Minthon L, Hansson O, Träskman-Bendz L, Brundin L
Abstract excerpt
OBJECTIVE: Recent studies indicate that inflammation may play a role in the pathophysiology of suicidality. Interleukin-8 (IL-8) is a chemokine that in addition to its function in the immune system also exert neuroprotective properties. The involvement of this chemokine in neuropsychiatric conditions is incompletely known. METHOD: We measured plasma and cerebrospinal fluid (CSF) IL-8, as well as the genotype...
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