Article
Development and application of an AllGlo probe-based qPCR assay for detecting knockdown resistance (kdr) mutations in Anopheles sinensis.
Malaria journal - 23 Sept 2014
Bai Liang, Zhu Guo-ding, Zhou Hua-yun, Tang Jian-xia, Li Ju-lin, Xu Sui, Zhang Mei-hua, Yao Li-nong, Huang Guang-quan, Wang Yong-bin, Zhang Hong-wei, Wang Si-bao, Cao Jun, Gao Qi
Abstract excerpt
BACKGROUND: Anopheles sinensis is one of the most important malaria vectors in China and other Southeast Asian countries. High levels of resistance have been reported in this species due to the long-term use of insecticides, especially pyrethroids, for public health and agricultural purposes. Knockdown resistance (kdr) caused by a single base pair mutation in the gene encoding the sodium channel is strongly...
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