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Development of a multiplex SNaPshot assay for simultaneous detection of multiple insecticide-resistance mutations in Anopheles sinensis.

Parasites & vectors - 19 Feb 2026

Xin Yi, Yue Zhenyu, Yan Shuning, Yu Chenghang, Liu Mowen, Yang Shuo, Xie Ruili, Zheng Bin, Yin Jianhai, Xu Bin

Abstract excerpt

BACKGROUND: Anopheles sinensis, the primary malaria vector in China, is a potential threat to the prevention of re-establishment of malaria transmission following imported cases. The extensive use of insecticides has led to widespread resistance. Conventional bioassays and molecular detection are limited in sensitivity, throughput, and efficiency, underscoring the need for a rapid and cost-effective genotyping...

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PMID: 41715232
DOI: 10.1186/s13071-026-07250-2
PMCID: PMC13020337

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