Article
First detection of multiple knockdown resistance (kdr)-like mutations in voltage-gated sodium channel using three new genotyping methods in Anopheles sinensis from Guangxi Province, China.
Journal of medical entomology - 1 Sept 2012
Tan Wei L, Li Chun X, Wang Zhong M, Liu Mei D, Dong Yan D, Feng Xiang Y, Wu Zhi M, Guo Xiao X, Xing Dan, Zhang Ying M, Wang Zhong C, Zhao Tong Y
Abstract excerpt
To investigate knockdown resistance (kdr)-like mutations associated with pyrethroid resistance in Anopheles sinensis (Wiedemann, 1828), from Guangxi province, southwest China, a segment of a sodium channel gene was sequenced and genotyped using three new genotyping assays. Direct sequencing revealed the presence of TTG-to-TCG and TG-to-TTT mutations at allele position L1014, which led to L1014S and L1014F...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.