Article
Calcium is the switch in the moonlighting dual function of the ligand-activated receptor kinase phytosulfokine receptor 1.
Cell communication and signaling : CCS - 23 Sept 2014
Muleya Victor, Wheeler Janet I, Ruzvidzo Oziniel, Freihat Lubna, Manallack David T, Gehring Chris, Irving Helen R
Abstract excerpt
BACKGROUND: A number of receptor kinases contain guanylate cyclase (GC) catalytic centres encapsulated in the cytosolic kinase domain. A prototypical example is the phytosulfokine receptor 1 (PSKR1) that is involved in regulating growth responses in plants. PSKR1 contains both kinase and GC activities however the underlying mechanisms regulating the dual functions have remained elusive. FINDINGS: Here, we confirm...
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