Article
Allosteric receptor activation by the plant peptide hormone phytosulfokine.
Nature - 10 Sept 2015
Wang Jizong, Li Hongju, Han Zhifu, Zhang Heqiao, Wang Tong, Lin Guangzhong, Chang Junbiao, Yang Weicai, Chai Jijie
Abstract excerpt
Phytosulfokine (PSK) is a disulfated pentapeptide that has a ubiquitous role in plant growth and development. PSK is perceived by its receptor PSKR, a leucine-rich repeat receptor kinase (LRR-RK). The mechanisms underlying the recognition of PSK, the activation of PSKR and the identity of the components downstream of the initial binding remain elusive. Here we report the crystal structures of the extracellular...
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