GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution.

doi:10.1007/s00277-014-2208-8

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Article

GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution.

Annals of hematology - 1 Feb 2015

Hou Hsin-An, Lin Yun-Chu, Kuo Yuan-Yeh, Chou Wen-Chien, Lin Chien-Chin, Liu Chieh-Yu, Chen Chien-Yuan, Lin Liang-In, Tseng Mei-Hsuan, Huang Chi-Fei, Chiang Ying-Chieh, Liu Ming-Chih, Liu Chia-Wen, Tang Jih-Luh, Yao Ming, Huang Shang-Yi, Ko Bor-Sheng, Hsu Szu-Chun, Wu Shang-Ju, Tsay Woei, Chen Yao-Chang, Tien Hwei-Fang

Abstract excerpt

Recently, mutations of the GATA binding protein 2 (GATA2) gene were identified in acute myeloid leukemia (AML) patients with CEBPA double mutations (CEBPA (double-mut)), but the interaction of this mutation with other genetic alterations and its dynamic changes during disease progression remain to be determined. In this study, 14 different missense GATA2 mutations, which were all clustered in the highly conserved...

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PMID: 25241285
DOI: 10.1007/s00277-014-2208-8

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GATA2
NPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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