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Article

A primate-specific functional GTTT-repeat in the core promoter of CYTH4 is linked to bipolar disorder in human.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Jan 2015

Rezazadeh M, Gharesouran J, Mirabzadeh A, Khorram Khorshid H R, Biglarian A, Ohadi M

Abstract excerpt

Evidence of primate-specific genes and gene regulatory mechanisms linked to bipolar disorder (BD) lend support to evolutionary/adaptive processes in the pathogenesis of this disorder. Following a genome-scale analysis of the entire protein coding genes annotated in the GeneCards database, we have recently reported that cytohesin-4 (CYTH4) contains the longest tetra-nucleotide short tandem repeat (STR) identified...

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Identifiers

PMID: 25240857
DOI: 10.1016/j.pnpbp.2014.09.001

Genes

CYTH4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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