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Regulatory mutations in the A2M gene are involved in the mastitis susceptibility in dairy cows.

Animal genetics - 1 Feb 2014

Wang X G, Huang J M, Feng M Y, Ju Z H, Wang C F, Yang G W, Yuan J D, Zhong J F

Abstract excerpt

Mutations, such as single nucleotide polymorphisms (SNPs), in the 5′-flanking and microRNA (miRNA) regulatory regions may result in altered gene expression levels and cause diseases. Alpha-2-macroglobulin (A2M) has the function of binding host or foreign peptides and particles, and thereby serves as a defense barrier against pathogens in the plasma and tissues of animals. To investigate the functional markers of...

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PMID: 25237709
DOI: 10.1111/age.12099

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Regulatory mutations in the A2M gene are involved in the mastitis susceptibility in dairy cows.PMID 25237709Read ↗

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