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Article

Unconventional secretion of synuclein-γ promotes tumor cell invasion.

The FEBS journal - 1 Nov 2014

Liu Caiyun, Qu Like, Lian Shenyi, Tian Zhihua, Zhao Chuanke, Meng Lin, Shou Chengchao

Abstract excerpt

Synuclein-γ (SNCG) is a chaperone protein and exists mainly in the cytoplasm. SNCG confers chemoresistance, and is a potential unfavorable biomarker for multiple types of cancer. Our previous work demonstrated that SNCG could be detected in the serum of cancer patients and the medium of cultured cancer cells, but the mechanism of SNCG secretion and its biological roles are unknown. Here, we showed that SNCG...

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Identifiers

PMID: 25229320
DOI: 10.1111/febs.13055

Genes

SNCG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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