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Article

Loss of Epigenetic Control of <i>Synuclein-γ</i> Gene as a Molecular Indicator of Metastasis in a Wide Range of Human Cancers

1 Sept 2005

Abstract excerpt

Metastasis is a major contributing factor to poor prognosis in cancer. Reliable and sensitive biomarkers that indicate the development of metastasis of primary tumors would be of great clinical use. In this study, we show that the neuronal protein synuclein-gamma (SNCG) is abnormally expressed in a high percentage (67.5%) of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric,...

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PMID: 16140929
DOI: 10.1158/0008-5472.can-05-1089

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