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Article

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.

Oncotarget - 30 Sept 2014

Nishi Mayuko, Akutsu Hidenori, Kudoh Ayumi, Kimura Hirokazu, Yamamoto Naoki, Umezawa Akihiro, Lee Sam W, Ryo Akihide

Abstract excerpt

Cancer stem cells (CSCs) retain the capacity to propagate themselves through self-renewal and to produce heterogeneous lineages of cancer cells constituting the tumor. Novel drugs that target CSCs can potentially eliminate the tumor initiating cell population therefore resulting in complete cure of the cancer. We recently established a CSC-like model using induced pluripotent stem cell (iPSC) technology to...

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Identifiers

PMID: 25228591
DOI: 10.18632/oncotarget.2356
PMCID: PMC4226712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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