Article
ABCA1 rs1883025 polymorphism shows no association with neovascular age-related macular degeneration or polypoidal choroidal vasculopathy in a Northern Chinese population.
Ophthalmic research - 1 Jan 2014
Li Fangting, Li Yingjie, Li Mingwu, Sun Yaoyao, Bai Yujing, Yang Fei, Guo Jing, Chen Yi, Huang Lvzhen, Li Xiaoxin
Abstract excerpt
PURPOSE: To analyze the association between ABCA1 rs1883025 variants with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) in a northern Chinese population. METHODS: The study enrolled 900 subjects, including 300 controls, 300 cases with nAMD and 300 cases with PCV. Genomic DNA was extracted from venous blood leukocytes. Single-nucleotide polymorphisms in the ABCA1...
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