Article
Association between the XRCC1 Arg194Trp polymorphism and glioma risk: an updated meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Xu Cheng, Chen Pin, Liu Wei, Gu Ai-Hua, Wang Xin-Ru
Abstract excerpt
Gliomas are the most common type of primary brain tumors. The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA) binding region, which suggests that this mutation may contribute to gliomagenesis and a number of articles have examine the association between XRCC1 Arg194Trp and the susceptibility to glioma. However, the results were conflicting. Test of heterogeneity, sensitivity...
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