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Article

Genetic prediction of antidepressant drug response and nonresponse in Korean patients.

PloS one - 1 Jan 2014

Lim Shinn-Won, Won Hong-Hee, Kim Hyeran, Myung Woojae, Kim Seonwoo, Kim Ka-Kyung, Carroll Bernard J, Kim Jong-Won, Kim Doh Kwan

Abstract excerpt

Genetic polymorphism contributes to variation in response to drug treatment of depression. We conducted three independent 6-week treatment studies in outpatients with major depressive disorder (MDD) to develop a pharmacogenomic model predicting response and nonresponse. We screened candidate genomic markers for association with response to selective serotonin reuptake inhibitors (SSRIs). No patients had received...

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Identifiers

PMID: 25226239
DOI: 10.1371/journal.pone.0107098
PMCID: PMC4166419

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