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Article

A functional p53 responsive polymorphism in KITLG, rs4590952, does not affect the risk of breast cancer.

Scientific reports - 15 Sept 2014

Chen Wei, Li Jiaoyuan, Liu Cheng, Chen Xueqin, Zhu Ying, Yang Yang, Gong Yajie, Wang Tengfei, Miao Xiaoping, Nie Xiu

Abstract excerpt

Recently, a functional polymorphism in KITLG, rs4590952, was identified to be associated with testicular cancer susceptibility through increasing the p53-dependent KITLG expression and disrupting the function of p53. We performed a hospital-based case-control study, including 1241 breast cancer (BC) patients and 1259 cancer-free controls, to investigate the role of this polymorphism in the risk of BC in Chinese...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25220285
DOI: 10.1038/srep06371
PMCID: PMC4163669

Genes

KITLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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