Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Known and new hemoglobin A2 variants in Thailand and implication for β-thalassemia screening.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2015

Panyasai Sitthichai, Fucharoen Goonnapa, Fucharoen Supan

Abstract excerpt

BACKGROUND: We reported molecular and hematological characteristics of δ-globin chain variants and addressed diagnostic consideration of complex hemoglobinopathies caused by their interactions with α- and β-thalassemias. METHODS: Study was done on four unrelated Thai subjects with second Hb A2 fractions. Hb analysis was carried out using automated HPLC and capillary electrophoresis. Mutations were identified by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Thalassemia
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobin A2

Share to Hemoglobins, Abnormal

Share to Infant

Share to Mass Screening

Share to Polymorphism, Restriction Fragment Length

Share to Thailand

Source

Identifiers

PMID: 25218786
DOI: 10.1016/j.cca.2014.09.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Known and new hemoglobin A2 variants in Thailand and implication for β-thalassemia screening.PMID 25218786Read ↗

Association of Hb A2 Variants with Several Forms of α- and β-Thalassemia in Thailand.Semantic proximity Read ↗

Prospective screening for δ-hemoglobinopathies associated with decreased hemoglobin A2 levels or hemoglobin A2 variants: A single center experience.Semantic proximity Read ↗

Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β-Thalassemia Screening.Semantic proximity Read ↗

Molecular Characterization of β- and α-Globin Gene Mutations in Individuals with Borderline Hb A2 Levels.Semantic proximity Read ↗

Hematological and Molecular Characterization of a Novel Hb A2 Variant with Homozygous α-Thalassemia-2 in a Southern Thai Individual.Semantic proximity Read ↗

δ-Hemoglobinopathies in Thailand: screening, molecular basis, genotype-phenotype interaction, and implication for prevention and control of thalassemia.Semantic proximity Read ↗

A large cohort of hemoglobin variants in Thailand: molecular epidemiological study and diagnostic consideration.Semantic proximity Read ↗

Common hemoglobin variants affecting the diagnosis of β-thalassemia: A large cohort data at a single center.Semantic proximity Read ↗

Five hemoglobin variants in a double heterozygote for α- and β-globin chain defects.Semantic proximity Read ↗

Compound Heterozygous Hemoglobin Minneapolis-Laos and Codon 41/42 (-TTCT) in a Thai Female Adult: A Case Report and Literature Review.Semantic proximity Read ↗

Clinical presentation and molecular identification of four uncommon alpha globin variants in Thailand. Initiation codon mutation of α2-globin Gene (HBA2:c.1delA), donor splice site mutation of α1-globin gene (IVSI-1, HBA1:c.95 + 1G>A), hemoglobin Queens Park/Chao Pra Ya (HBA1:c.98T>A) and hemoglobin Westmead (HBA2:c.369C>G).Semantic proximity Read ↗

Elevated Hb A2 is Not Always Indicative of β-Thalassemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.