Article
Association of Hb A2 Variants with Several Forms of α- and β-Thalassemia in Thailand.
Hemoglobin - 1 May 2020
Panyasai Sitthichai, Pornprasert Sakorn
Abstract excerpt
In this study, Hb A2 variants and their association with α- and β-thalassemia (α- and β-thal) were analyzed. We performed molecular analyses to identify α-thal [- -SEA (Southeast Asian), - -THAI (Thai), -α3.7 (rightward) and -α4.2 (leftward)] deletions, and Hb Constant Spring (Hb CS; HBA2: c.427T>C), Hb A2-Melbourne (HBD: c.130G>A), Hb A2' (HBD: c.49G>C), Hb A2-Lampang (HBD: c.142G>A). β0-Thalassemia mutations...
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