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Association of DNA Methylation and Mitochondrial DNA Copy Number with Human Semen Quality1

11 Sept 2014

Abstract excerpt

Whether there is a relationship between quality, DNA methylation, and mitochondrial DNA (mtDNA) copy number in human-derived sperm specimens is unknown. A cohort (n = 118) of male partners of couples who were undergoing fertility assessment because of an idiopathic inability to conceive were recruited. Sperm motility parameters were determined by computer-aided sperm analysis (CASA), while sperm quality was...

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PMID: 25210131
DOI: 10.1095/biolreprod.114.122465

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