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Article

Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas.

Advances in experimental medicine and biology - 1 Jan 2014

Albert Benedikt, Hahn Heidi

Abstract excerpt

Basal Cell Carcinomas (BCCs) are the most commonly diagnosed tumors among people in the western world. Most BCCs are caused by mutational inactivation of the tumor suppressor Patched (PTCH), which results in activation of Smoothened (SMO) and of the Hedgehog (HH) signaling pathway. Recent studies indicate that BCC progression involves a crosstalk between Hh signaling, vitamin D derivatives and the vitamin D...

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Share to Carcinoma, Basal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Calcitriol

Share to Receptors, G-Protein-Coupled

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Source

Identifiers

PMID: 25207374
DOI: 10.1007/978-1-4939-0437-2_18

Genes

SMO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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