Article
The power of genes: a case of unusually severe systemic toxicity after localized hepatic chemoembolization with irinotecan-eluted microspheres for metastatic colon cancer.
The Annals of pharmacotherapy - 1 Dec 2014
Cruz Joseph E, Saksena Rujuta, Jabbour Salma K, Nosher John L, Hermes-DeSantis Evelyn, Moss Rebecca A
Abstract excerpt
OBJECTIVE: To report a case of systemic irinotecan toxicity following regional transarterial chemoembolization with drug-eluting beads loaded with irinotecan (DEBIRI-TACE) in a patient later found to have a homozygous mutation for UGT1A1*28. CASE SUMMARY: An 80-year-old woman presented with a cec...
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