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Article

Virus infection triggers widespread silencing of host genes by a distinct class of endogenous siRNAs in Arabidopsis.

Proceedings of the National Academy of Sciences of the United States of America - 7 Oct 2014

Cao Mengji, Du Peng, Wang Xianbing, Yu Yun-Qi, Qiu Yan-Hong, Li Wanxiang, Gal-On Amit, Zhou Changyong, Li Yi, Ding Shou-Wei

Abstract excerpt

Antiviral immunity controlled by RNA interference (RNAi) in plants and animals is thought to specifically target only viral RNAs by the virus-derived small interfering RNAs (siRNAs). Here we show that activation of antiviral RNAi in Arabidopsis plants is accompanied by the production of an abundant class of endogenous siRNAs mapped to the exon regions of more than 1,000 host genes and rRNA. These virus-activated...

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Identifiers

PMID: 25201959
DOI: 10.1073/pnas.1407131111
PMCID: PMC4209997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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