Article
Identification of a New Host Factor Required for Antiviral RNAi and Amplification of Viral siRNAs.
Plant physiology - 1 Feb 2018
Guo Zhongxin, Wang Xian-Bing, Wang Ying, Li Wan-Xiang, Gal-On Amit, Ding Shou-Wei
Abstract excerpt
Small interfering RNAs (siRNAs) are processed from virus-specific dsRNA to direct antiviral RNA interference (RNAi) in diverse eukaryotic hosts. We have recently performed a sensitized genetic screen in Arabidopsis (Arabidopsis thaliana) and identified two related phospholipid flippases required for antiviral RNAi and the amplification of virus-derived siRNAs by plant RNA-dependent RNA polymerase1 (RDR1) and...
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