Article
The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana.
The Plant cell - 1 Apr 2011
Wang Xian-Bing, Jovel Juan, Udomporn Petchthai, Wang Ying, Wu Qingfa, Li Wan-Xiang, Gasciolli Virginie, Vaucheret Herve, Ding Shou-Wei
Abstract excerpt
Arabidopsis thaliana defense against distinct positive-strand RNA viruses requires production of virus-derived secondary small interfering RNAs (siRNAs) by multiple RNA-dependent RNA polymerases. However, little is known about the biogenesis pathway and effector mechanism of viral secondary siRNAs. Here, we describe a mutant of Cucumber mosaic virus (CMV-Δ2b) that is silenced predominantly by the RNA-DEPENDENT...
Topics
- Antiviral Agents
- Arabidopsis
- Arabidopsis Proteins
- Argonaute Proteins
- Cucumovirus
- Gene Silencing
- Immunity, Innate
- Mutation
- Nucleotides
- Plant Diseases