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Article

TYMV and TRV infect Arabidopsis thaliana by expressing weak suppressors of RNA silencing and inducing host RNASE THREE LIKE1.

PLoS pathogens - 1 Jan 2023

Sehki Hayat, Yu Agnès, Elmayan Taline, Vaucheret Hervé

Abstract excerpt

Post-Transcriptional Gene Silencing (PTGS) is a defense mechanism that targets invading nucleic acids of endogenous (transposons) or exogenous (pathogens, transgenes) origins. During plant infection by viruses, virus-derived primary siRNAs target viral RNAs, resulting in both destruction of single-stranded viral RNAs (execution step) and production of secondary siRNAs (amplification step), which maximizes the...

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PMID: 36696453
DOI: 10.1371/journal.ppat.1010482
PMCID: PMC9901757

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